General Cell Based Assays
Arbor Assays Glutathione Colorimetric Detection Kit (4 Plate)
The DetectX Glutathione (GSH) Detection Assay Kits allow for convenient, rapid, and easy quantitation of both GSH and GSSG for an accurate measurement of a cell's oxidative status in a variety of sample types.
Cayman Chemical pn-TrkC-Term RabbIt Monc 100uL
A positive allosteric modulator of M1 mAChRs increases ACh-induced calcium flux in CHO cells expressing human M1 receptors (EC50 21 nM) reverses scopolamine-induced cognitive deficits in an object retrieval detour task in rhesus macaques at 0 3 and 1 mg/kg
Eurofins Discoverx PathHunter eXpress CHRM2 Activated GPCR Internalization Assay, 2pl Kit. (93-0656E3CP5M)
The PathHunter CHRM2 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CHRM2 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CHRM2. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CHRM2-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx InCELL Hunter eXpress BLK Kinase Binding Assay, 2pl Kit. (96-0044E1CP0M)
The InCELL Hunter eXpress BLK Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of BLK via detection of BLK levels. This product uses EFC technology. The cell line included overexpresses BLK target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Aat Bioquest Cell Navigator Lysosome Staining Kit Green Fluorescence (500 Tests)
Our Cell Navigator fluorescence imaging kits are a set of fluorescence imaging tools for labeling sub-cellular organelles such as membranes lysosomes mitochondria and nuclei etc. This catalog is for 500 Tests.
Cayman Chemical CelBased asy MyeloperoxId 50uL
A peptide hormone selectively binds to MC1R over MC3R MC4R and MC5R (Kis 0.89 10.64 8.18 and 76.9 nM respectively) induces lipolysis in isolated rabbit adipocytes at 1 UM increases plasma levels of glucagon insulin and free fatty acids in fed or fasted rabbits at 45 UG/animal CSF levels are increased in patients with restless legs syndrome with painful symptoms
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-p70 S6K (Thr389) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-p70 S6K (Thr389) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Phospho-NDRG1 (Thr346) Detection Kit, 500 Assay Points
HTRF Phospho-NDRG1 (Thr346) Detection Kit, 500 Assay Points
Molecular Devices cAMP Fluorescent Assay Kit, 384-Well, Bulk, 60 μL
The CatchPoint cAMP Fluorescent Assay Kit is a high-throughput competitive immunoassay for quantifying 3',5'-cyclic adenosine monophosphate (cAMP) and measuring adenylate cyclase activity in biochemical and cell-based assays. The 384-well bulk format supplies reagents for 20 plates (7,680 assay points) and is optimized for fluorescence intensity detection with long signal stability.
- 384-well bulk format, sufficient for 20 plates (7,680 wells)
- Reaction volume 60 μL per well, 50 μL supported for some HTS systems
- Fluorescence intensity detection using Stoplight Red substrate
- Minimum detectable concentration 0.1 nM (6 fmol/well), EC50 approximately 3.4 nM
- Readings stable from 10 minutes up to 24 hours after substrate addition
- Store components at 4°C; kit components stable for six months when stored properly
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-FOXO1 (Ser256) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-FOXO1 (Ser256) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc AlphaScreen cAMP Detection Kit, 10,000 Assay Points
AlphaScreen cAMP Detection Kit, 10,000 Assay Points
Glass Expansion D-Torch Pro Duo with 2.0mm Quartz Injector
D-Torch complete assembly with 2.0mm ID quartz injector & installation guide. Compatible with Thermo PRO Duo ICP-OES.A patented, precision-engineered, demountable torch, incorporating a ceramic inner tube for greater robustness & demountable quartz outer tube that can be replaced when it fails rather than replacing the entire torch. D-Torch also features an interchangeable injector, allowing installation of a specific injector, whether it be for aqueous (~2.0mm ID), organics (<2.0mm ID), high TDS (>2.0mm ID) or HF (alumina). Compatible with all EMT injectors.The D-Torch is the only design with an optional ceramic outer tube (P/N NC2046972). The quartz outer tube is ideal for most applications while the ceramic outer tube is best for high TDS, organics, or HF matrices. Replacement parts include 31-808-4125, NC2046973, NC2046972, 50-169-4654, 31-808-2707, 31-808-2895, 31-808-2897, 70-803-1520.Glass Expansion is ISO 9001:2015 certified by AB Certification, No. AU4501-9001
Eurofins Discoverx PathHunter Mouse CRHR1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse CRHR1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CRHR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cell Biolabs Inc NAD+/NADH Assay Kit (Colorimetric), 100 assays
Cell Biolabs’ NAD+/NADH Assay Kit (Colorimetric) is a simple assay that measures NAD+ and NADH present in biological samples such as cell lysates or tissue extracts in a 96-well microtiter plate format. The kit is specific for NAD+, NADH, and their ratio. The kit will not detect NADP+ or NADPH. The total NAD+/NADH concentrations of unknown samples are determined by comparison with a known NAD+ standard. Determination of both NAD+ and NADH requires two separate samples for quantification. NAD+ and NADH do not need to be purified from samples, but rather can be extracted individually with a simple acid or base treatment prior to performing the assay. The kit has a detection sensitivity limit of approximately 4 nM NAD+. Each kit provides sufficient reagents to perform up to 100 assays, including blanks, NAD+ standards and unknown samples.
ACROBiosystems Human Fc gamma RIIIA / CD16a (F176) binding Kit (TR-FRET) is expressed from Human, 10000 tests
Human Fc gamma RIIIA / CD16a (F176) binding Kit (TR-FRET) is expressed from Human